202Jude M. Phillip, Pei-Hsun Wu, Daniele M. Gilkes, Wadsworth Williams, Shaun McGovern, Jena Daya, Jonathan Chen, Ivie Aifuwa, Jerry S. H. Lee, Rong Fan, Jeremy Walston
and Denis Wirtz
Biophysical and biomolecular determination of
cellular age in humans
Nature Biomedical Engineeringpdf2017
201Julia A. Ju, Ines Godet, I Chae Ye, Jungmin Byun
, Hasini Jayatilaka
, Sun Joo Lee, Lisha Xiang, Debangshu Samanta, Meng Horng Lee, Pei-Hsun Wu, Denis Wirtz, Gregg L. Semenza, and Daniele M. Gilkes
Hypoxia Selectively Enhances Integrin a5b1 Receptor Expression in Breast Cancer to Promote MetastasisMolecular Cancer Researchpdf2017
200Tainia Perestrelo, Weitong Chen, Marcelo Correia, Christopher Le, Sandro Pereira, Ana S. Rodrigues, Maria I. Sousa, Joao Ramalho-Santos, and Denis WirtzPluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through
an Image-Based Analysis Software
Stem Cell Reportspdf2017
199Lijuan He, Jiaxiang Tao, Fangwei Si, Yi Wu, Tiffany Wu, Vishnu Prasath,
Denis Wirtz, and Sean X. Sun
Role of Membrane-tension Gated Ca Flux in Cell MechanosensationBioRXivpdf2017
198L. He, A. Sneider, W. Chen, M. Karl, V. Prasath, P.-H. Wu, G. Mattson, and D. WirtzMammalian cell Division in 3D matrices via quantitative confocal reflection microscopyJournal of Visual Experimentsto appear2017
197Hasini Jayatilaka, Pranay Tyle, Jonathan J. Chen, Minsuk Kwak, Julia J u,Hyun Ji Kim, Jerry S.H. Lee, Pei-Hsun Wu, Daniele M. Gilkes, Rong Fan, Denis WirtzSynergistic IL-6 and IL-8 paracrine signalling pathwy infers a strategy to inhibit tumour cell migrationNature Communicationspdf2017
196Y. Wang, J. Gong, D. Wirtz, and B.W. Schafer,Affine and non-affine deformations quantified in cytoskeletal networks through three-dimensional form-finding modelMechanical Behavior of Biomedical Materialspdf2017
195H. Jayatilaka, P. Tyle, J.J. Chen, M. Kwak, J.A. Ju, H.J. Kim, J.S.H. Lee, P.-H. Wu, D.M. Gilkes, R. Fan, and D. WirtzNovel synergistic IL6/8 paracrine signaling pathway infers new strategy to inhibit tumor cell migration Nature Communications to appear2017Cell migration
194J.A. Ju, I. Godet, I.C. Ye, J. Byun, H. Jayatilaka, S. J. Lee, L. Xiang, D. Samanta, M.H. Lee, P.-H. Wu, D. Wirtz, G.L. Semenza, and D.M. GilkesHypoxia selectively enhances integrin receptor expression to promote metastasisMolecular Cancer Researchto appear2017
193H Ahmadzadeh, M R Webster, A M Jimenez Valencia, D Wirtz, A T Weeraratna, V B ShenoyModeling the Two-way Feedback Between Contractility and Matrix Realignment Reveals a Non-linear Mode of Cancer Cell InvasionProceedings of the National Academy of Sciences pdf2017Cell invasion, Cell contractility, Matrix realignment, Rho-pathway
192D. M. Gilkes and D. WirtzCutting the stress outNature Biomedical Engineering pdf2017Tumour mechanopathology
191A. Agarwal, P-H Wu, E.G. Hughes, M. Fukaya, M.A. Tischfield, A. Langseth,D. Wirtz, D.E. BerglesTransient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte ProcessesNeuron pdf2017
190W-C. Hung, J.Wang, C. Yankaskas, B.S. Wang, P-H. Wu, C. Pardo-Pastor, S. Serra, M.J. Chiang, Z. Gu, M. Valverde, D. Wirtz, J. Yang, J. Zhang, K. Konstantopoulos

Confinement-sensing and Signal Optimization via Piezo1/PKA and Myosin II pathwaysCell Reports pdf2016
189J. Licht, M. Shah, E. Martinez-Garcia, J. Phillip, A. Chambliss, R. Popovic, T. Ezponda, E. Small, C. Will, M. Phillip, P. Neri, N. Bahlis, and D. WirtzMMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agentsOncogene pdf2016DNA damage, MMSET/WHSC1
188Y. Gua, S-L Chiu, B. Liua, P-H Wu, M. Delannoy, D-T Lin, D. Wirtz and R. L. HuganirDifferential vesicular sorting of AMPA and
GABAA receptors
Proceedings of the National Academy of Sciences pdf2016AMPA receptor, GABAA receptor, constitutive exocytosis, TIRFM, SNARE
187V.C. Hecht, L.B. Sullivan, R.J. Kimmerling, D.-H. Kim, A.M. Hosios, 
M.A. Stockslager, M.M. Stevens, J.H. Kang, D. Wirtz, M.G. Vander Heiden, and S.R. ManalisBiophysical changes reduce energetic demand in growth factor–deprived lymphocytesJournal of Cell biology pdf2016
186P-H.Wu, J. M. Phillip, S. B. Khatau, W-C. Chen, J. Stirman, S. Rosseel, K. Tschudi, J. V. Patten, M. Wong, S. Gupta, A. S. Baras, J. T. Leek, A. Maitra, D. WirtzEvolution of cellular morphophenotypes
in cancer metastasis
Scientific Reports pdf2015Pancreatic ductal adenocarcinoma, cell phenotyping
185J. S. Sarnecki, K, H. Burns, L. D. Wood, K. M. Waters, R. H. Hruban, D. Wirtz, and P. WuA robust non-linear tissue-component discrimination method for computational pathologyLaboratory Investigation pdf2015Digital pathology, Image analysis
184L. He, W. Chen, P.-H. Wu, A. Jimenez, B.S. Wong, A. San, K. Konstantopoulos, D. WirtzLocal 3D matrix confinement determines division axis through cell shapeOncotarget pdf2015 3D matrix, elongated cell division, long-axis rule, matrix confinement
183Angela M. Jimenez Valencia, Pei-Hsun Wu, Osman N. Yogurtcu, Pranay Rao, Josh DiGiacomo, Inês Godet, Lijuan He, Meng-Horng Lee, Daniele Gilkes, Sean X. Sun, Denis WirtzCollective cancer cell invasion induced by coordinated contractile stressesOncotarget pdf2015
182I. Aifuwa, A. Giri, N. Longe, S.H. Lee, S. S. An, D. Wirtz Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractilityOncotarget pdf2015SASP, senescence
181S.I. Fraley, P.-H. Wu, L. He, Y. Feng, R. Krisnamurthy, G.D. Longmore, and D. WirtzThree-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusionsScientific Reports pdf20153D motility, MMP, ECM
180D.-H. Kim, B. Li, F. Si, J. Philip, D. Wirtz, and S.X. SunVolume regulation and shape bifurcation in the cell nucleusJournal of Cell Science pdf2015Cell nucleus, Volume change, Mechanics,
179B. Palmieri, Y. Bresler, D. Wirtz, and M. GrantMultiscale model for cell migration in monolayers: elastic mismatch between cells enhanced motilityScientific Reports pdf2015cell migration, cell monolayer
178M.-H. Lee, P.-H. Wu, D. Gilkes, I. Aifuwa, and D. WirtzNormal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusionsOncotarget pdf2015 cancer invasion, cell-cell interaction, protrusion
177D.J. Shea, D. Wirtz, K.J. Stebe and K. KonstantopoulosKinetic and mechanical properties govern Mucin 16- and Podocalyxin- mediated tumor cell adhesion to E- and L-selectin in shear FlowOncotarget pdf2015 Mucin16, PODXL, selectin, off-rate, pancreatic cancer
176Y. Yu, S. Gaillard, J.M. Phillip, T.-C. Huang, S.M Pinto, N.G. Tessarollo, Z. Zhang, A. Pandey, D. Wirtz, A. Ayhan, B. Davidson, T.-L. Wang, and I.-M. Shihnhibition of spleen tyrosine kinase potentiates paclitaxel-induced cytotoxicity in ovarian cancer cells by stabilizing microtubulesCancer Cell pdf2015SYK, microtubules, paclitaxel
175J. M. Phillip, I. Aifuwa, J.Walston, and D. WirtzThe Mechanobiology of AgingAnnual Review of Biomedical Engineering pdf2015cellular mechanics, nuclear mechanics, extracellular matrix, mitochondrial
174D.-H. Kim, D. WirtzCytoskeletal tension induces the 3D polarized architecture of the nucleusBiomaterials pdf2015nuclear lamina, LINC complex, actin cap
173A.-R. Yoon, I. Stasinopoulos, J.H. Kim, H.M. Yong, O. Kilic, D. Wirtz, Z. Bhujwalla, and S.S. AnCOX-2 dependent regulation of mechanotransduction in human breast cancer cellsCancer Biology and Therapy pdf2015COX-2, ECM, Mechanotransduction
172P.-H. Wu, A. Giri, and D. WirtzStatistical analysis of cell migration in 3D using the anisotropic persistent random walk modelNature Protocols pdf20153D cell motility, APRW model, protocol
171L. He and D. WirtzSwitching from protease-independent to protease-dependent cancer cellBiophysical Journal pdf2015metastasis, ecm
170D. Gilkes, G. Semenza, and D. WirtzHypoxia and the extracellular matrix: drivers of tumor metastasisNature Reviews Cancer pdf2014Hypoxia, metastasis, ecm
169K.M. Stroka, H. Jiang, Z. Tong, D. Wirtz, S.X. Sun, and K. KonstantopoulosWater permeation drives tumor cell migration in confined microenvironmentsCell pdf2014cell migration, cell volume, water permeation
168 D.-H. Kim, S. Cho, and D. WirtzTight coupling between nucleus and cell migration through the perinuclear actin capJournal of Cell Science pdf2014actin cap, migration, nucleus
167P.-H. Wu, A. Giri, S. X. Sun, D. WirtzThree-dimensional cell migration does not follow a random walkProceedings of the National Academy of Sciences pdf20143D, three-dimensional, APRW, anisotropic random walk
166K. M. A. Yong, Y. Zeng, D. Vindivich, J. M. Phillip, P.‰ÛH. Wu, D. Wirtz, R. H. GetzenbergMorphological Effects on Expression of Growth Differentiation Factor 15 (GDF15), a Marker of MetastasisJournal of cellular physiology pdf2014GDF15, metastasis
165D. M. Gilkes, L. Xiang, S. J. Lee, P. Chaturvedi, M. E. Hubbi, D. Wirtz, G. L .SemenzaHypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cellsProceedings of the National Academy of Sciences pdf2014ROCK1, breast cancer,
164D. Razafsky, D. Wirtz, D. HodzicNuclear envelope in nuclear positioning and cell migrationAdvances in experimental medicine and biology pdf2014nuclear envelope, nuclear positioning, cell migration
163Q. Guo, J. M. Phillip, S. Majumdar, P.-H. Wu, J. Chen, X. CalderÌ_n-ColÌ_n, O. Schein, B. J. Smith, M. M. Trexler, D. Wirtz, J. H. ElisseeffModulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repairBiomaterials pdf2013collagen, keratocyte
162T. M. Dobrowsky, S. A. Rabi, R. Nedellec, B. R. Daniels, J. I. Mullins, D. E. Mosier, R. F. Siliciano, D. WirtzAdhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteinsScientific reports pdf2013HIV-1, surface proteins
161A. Giri, S. Bajpai, N. Trenton, H. Jayatilaka, G. D. Longmore, D. WirtzThe Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migrationThe FASEB Journal pdf2013Arp2/3, 3D, cell migration, protrusions
160A. B. Chambliss, P.-H. Wu, W. C. Chen, S. X. Sun, D. WirtzSimultaneously defining cell phenotypes, cell cycle, and chromatin modifications at single-cell resolutionThe FASEB Journal pdf2013cell cycle, cell phenotypes, chromatin modifications, epigenetics
159D. M. Gilkes, Pallavi Chaturvedi, S. Bajpai, C. C. Wong, H. Wei, S. Pitcairn, M. E. Hubbi, D. Wirtz, G. L. SemenzaCollagen prolyl hydroxylases are essential for breast cancer metastasisCancer research pdf2013collagen, prolyl hydroxylases
158D.-H. Kim, A. B. Chambliss, D. WirtzThe multi-faceted role of the actin cap in cellular mechanosensation and mechanotransductionSoft matter pdf2013actin cap, mechanotransduction, mechanosensation
157D. M. Gilkes, S. Bajpai, C. C. Wong, P.C haturvedi, M. E Hubbi, D. Wirtz, G. L. SemenzaProcollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasisMolecular Cancer Research pdf2013procollagen lysyl hydroxylase 2, hypoxia
156D.-H. Kim, D. WirtzPredicting how cells spread and migrate: Focal adhesion size does matterCell adhesion & migration pdf2013focal adhesions, cell migration
155TPSOC NetworkA physical sciences network characterization of non-tumorigenic and metastatic cellsScientific reports pdf2013metastasis, metastatic cell, PSOC
154DM Gilkes, S Bajpai, P Chaturvedi, D Wirtz, GL SemenzaHypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblastsJournal of Biological Chemistry pdf2013HIF-1, matrix remodeling
153D.-H. Kim, D. WirtzFocal adhesion size uniquely predicts cell migrationThe FASEB Journal pdf2013focal adhesions, cell migration
152D. WirtzInterstitial Friction Greatly Impacts Membrane MechanicsBiophysical Journal pdf2013interstitial friction, membrane mechanics
151Yao Lu, Jonathan J Chen, Luye Mu, Qiong Xue, Yu Wu, Pei-Hsun Wu, Jie Li, Alexander O Vortmeyer, Kathryn Miller-Jensen, Denis Wirtz, Rong FanHigh-throughput secretomic analysis of single cells to assess functional cellular heterogeneityAnalytical chemistry pdf2013secretomics, single cell, cellular heterogeneity
150K Konstantopoulos, PH Wu, D WirtzDimensional control of cancer cell migrationBiophysical Journal pdf2013cancer cell migration
149Allison B Chambliss, Shyam B Khatau, Nicholas Erdenberger, D Kyle Robinson, Didier Hodzic, Gregory D Longmore, Denis WirtzThe LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransductionScientific reports pdf2013LINC, actin cap, mechanotransduction
148S Bajpai, Y Feng, D Wirtz, GD Longmoreb-Catenin Serves as a Clutch between Low and High Intercellular E-Cadherin Bond StrengthsBiophysical Journal pdf2013b-catenin, e-cadherin bonds
147J Gong, D Zhang, Y Tseng, B Li, D Wirtz, BW SchaferForm-Finding Model Shows How Cytoskeleton Network Stiffness Is RealizedPloS one pdf2013cytoskeleton
146E.B. Stukalin, I. Aifuwa, J.S. Kim, D. Wirtz, S.X. SunAge-dependent stochastic models for understanding population fluctuations in continuously cultured cellsJournal of The Royal Society Interface pdf2013population fluctuations
145Wei-Chiang Chen, Pei-Hsun Wu, Jude M Phillip, Shyam B Khatau, Jae Min Choi, Matthew R Dallas, Konstantinos Konstantopoulos, Sean X Sun, Jerry SH Lee, Didier Hodzic, D. WirtzFunctional interplay between the cell cycle and cell phenotypesIntegrative Biology pdf2013interplay, cell cycle, cell phenotypes
144 E. Chau, J.F. Galloway, A. Nelson, P.N. Breysse, D. Wirtz, P.C. Searson, and V.K. SidhayeEffect of modifying quantum dot surface charge on airway epithelial cell uptake in vitroNanotoxicology pdf2012nanoparticles, quantum dots, airway epithelial cells
143K.L. Yap, S.I. Fraley, M.M. Thiaville, N. Jinawath, K. Nakayama, J.-L. Wang, T.- L. Wang, D. Wirtz, and I.-M. ShihNAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cellsCancer Research pdf2012NAC1, actin-binding protein
142P.S. Raman, C.S. Alves, D. Wirtz, and K. KonstantopoulosDistinct Kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen)Biophysical Journal pdf2012CD44
141D.-H. Kim, S.B. Khatau, Y. Feng, S. Walcott, S.X. Sun, G.D. Longmore, and D. WirtzActin cap associated focal adhesions and their distinct role in cellular mechanosensingScientific Reports (Nature) pdf2012actin cap, mechanosensing
140S.B. Khatau, R.J. Bloom, S. Bajpai, D. Razafsky, S. Zang, A. Giri, P.-H. Wu, J. Marchand, A. Celedon, C.M. Hale, S.X. Sun, D. Hodzic, and D. WirtzThe distinct roles of the nucleus and nucleus-cytoskeleton connections in three- dimensional cell migrationScientific Report (Nature) pdf2012actin cap, three-dimensional,nucleus-cytoskeleton
139M.-H. Lee, P.-H. Wu, J.R. Staunton, R. Ros, G.D. Longmore, and D. WirtzMismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayerBiophysical Journal pdf2012cancer, pulsating, migration
138) S.B. Khatau, S. Kusuma, D. Hanjaya-Putra, P. Mali, L. Cheng, J.S.H. Lee, S. Gerecht, and D. WirtzThe differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cellsPLOS One pdf2012actin cap, LINC, pluripotent
137M.R. Dallas, G. Liu, W.-C. Chen, S.N. Thomas, D. Wirtz, D.L. Huso, K. KonstantopoulosDivergent roles of CD44 and carcinoembryonic antigen in colon carcinoma metastasisFASEB Journal pdf2012CD44, carcinoembryonic, metastasis
136S.I. Fraley, Y. Feng, A. Giri, G.D. Longmore, and D. WirtzDimensional and temporal controls of cell migration by zyxin and binding partners in three-dimensional matrixNature Communications pdf2012zyxin, temporal control, three-dimensional, 3D, cell migration
135L.S.-L. Cheung, P.S. Raman, D. Wirtz and K. KonstantopoulosBiophysics of selectin-mediated cell‰ÛÒcell adhesionComprehensive biophysics pdf2012selectin
134D. WirtzBiophysics of molecular cell mechanicsComprehensive biophysics pdf2012cell mechanics
133D. WirtzCell Biophysics, IntroductionComprehensive biophysics pdf2012cell mechanics
132P.-H. Wu, C.M. Hale, J.S.H. Lee, Y. Tseng, and D. WirtzHigh-throughput ballistic injection nanorheology (htBIN) to measure cell mechanicsNature Protocols pdf2012htBIN, cell mechanics, ballistic injection
131C.M. Hale, W.-C. Chen, S.B. Khatau, B.R. Daniels, J.S.H. Lee, and D. WirtzSMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarizationJournal of Cell Science pdf2011
SMRT, MTOC, nuclear positioning
130S. Walcott, D.-H. Kim, D. Wirtz, S.X. SunNucleation and decay initiation are the stiffness-sensitive phases of focal adhesion maturationBiophysical Journal pdf2011nucleation and decay, focal adhesions
129A. Celedon, C.M. Hale, and D. WirtzMagnetic manipulation of nanorods in the nucleus of living cellsBiophysical Journal pdf2011magnetic, nanorods
128C. C. L. Wong, D. Gilkes, H. Zhang, J. Chen, H. Wei, P. Chaturvedi, S.I. Fraley, C.M. Wong U.-S. Khoo, I.O.L. Ng, D. Wirtz, and G.L. SemenzaHypoxia- Inducible Factor 1 is a master regulator of breast cancer metastatic niche formationProceedings of the National Academy of Sciences pdf2011HIF, breast cancer, metastasis
127D. Wirtz, K. Konstantopoulos, and P.C. SearsonPhysics of cancer: the role of physical interactions and mechanical forces in cancer metastasisNature Reviews pdf2011cancer, review, physics of cancer
126D.-H. Kim and D. WirtzRecapitulating cancer cell invasion in vitroProceedings of the National Academy of Sciences pdf2011cancer cell invasion
125S.I. Fraley, C.M. Hale, R.J. Bloom, A. Celedon, J.S.H. Lee, and D. WirtzIntra- and extracellular microrheology of endothelial cells in a 3D matrixBiological and Medical Physics, Biomedical Engineering pdf2011microrheology, endothelial cells
124P.S. Raman, C.S. Alves, D. Wirtz, K. KonstantopoulosSingle molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancerJournal of Cell Science pdf2011CD44, P-selectin
123J.S.H. Lee and D. WirtzPhysical OncologyPhysical Biology pdf2011
122L.S.-L. Cheung, P.S. Raman, E.M. Balzer, D. Wirtz, and K. KonstantopoulosBiophysics of selectin-ligand interactions in inflammation and cancerPhysical Biology pdf2011biophysics, selectin
121S. I. Fraley, Y. Feng, D. Wirtz and G.D. LongmoreReply: reducing background fluorescence reveals adhesions in 3D matricesNature Cell Biology pdf2011
120A. Celedon, D. Wirtz, and Sean X. SunTorsional mechanics of DNA are regulated by small-molecule intercalationJournal of Physical Chemistry pdf2010DNA, torsion, intercalation
119T.M. Dobrowsky and D. WirtzSingle-molecule analysis of cell-virus binding interactionsCell Signalling Reactions: Single-Molecular Kinetic Analysis pdf2010single-molecule, cell-virus,
118B.R. Daniels, C.M. Hale, S.B. Khatau, S. Kusuma, T.M. Dobrowsky, S. Gerecht, and D. WirtzThe difference in microrheology between human induced pluripotent stem (iPS) cells and human embryonic stem (hES) cellsBiophysical Journal pdf2010iPS, hES, microrheology
117P. Mali, D. Wirtz, and P.C. SearsonInterplay of RhoA and motility in the programmed spreading of daughter cells post mitosisBiophysical Journal pdf2010
116D. Wirtz and S.B. KhatauBundles from boundariesNature Materials pdf2010
115A. Dajkovic, S. Pichoff, J. Lutkenhaus, and D WirtzCross-linking FtsZ polymers into coherent Z ringsMolecular Microbiology pdf2010
114P.J. Stahl, N.H. Romano, D. Wirtz, and S.M. YuPEG-based hydrogels with collagen mimetic peptide-mediated and tunable physical cross-linksBiomacromolecules pdf2010
113B.R. Daniels, T.M. Dobrowsky, E.M. Perkins, S.X. Sun, and D. WirtzMEX-5 enrichment in C. elegans early embryos mediated by differential diffusionDevelopment pdf2010
112S. I. Fraley, Y. Feng, D.-H. Kim, A. Celedon, G.D. Longmore, and D. WirtzThe distinctive role of focal adhesion proteins in three-dimensional cell motilityNature Cell Biology pdf2010
111T.M. Dobrowsky, B.R. Daniels, R.F. Siliciano, S.X. Sun, and D. WirtzOrganization of cellular receptors into a nanoscale junction during HIV-1 adhesionPLOS Computational Biology pdf2010
110B. Wildt, D. Wirtz, and P.C. SearsonTriggering cell detachment from patterned electrode arrays by programmed subcellular releaseNature Protocols pdf2010
109S.B. Khatau, D.-H. Kim, C.M. Hale, and D. WirtzThe perinuclear actin cap in health and diseaseNucleus pdf2010
108E. Esue, L. Ruppercht, D. WirtzDynamics of the bacterial intermediate filament crescentin in vitro and in vivoPLOS One pdf2010
107S.B. Khatau, C.M. Hale, P.J. Stewart-Hutchinson, M.S. Patel, C.L. Stewart, P.C. Searson, D. Hodzic, and D WirtzA perinuclear actin cap regulates nuclear shapeProceedings of the National Academy of Sciences pdf2009
106C.M. Hale, S.X. Sun, and D. WirtzResolving the role of actomyosin contractility in cell microrheologyPLOS One pdf2009
105J.F. Galloway, J. Park, K.H. Lee, D. Wirtz, and P.C. SearsonExploiting nucleation and growth in the synthesis and electrical passivation of CdSe quantum dotsScience of Advanced Materials pdf2009
104S. Bajpai, Y. Feng, R. Krishnamurthy, G.D. Longmore, and D. WirtzLoss of ë±- catenin decreases the strength of single E-cadherin bonds between human cancer cellsJournal of Biological Chemistry pdf2009
103D. WirtzParticle tracking microrheology of living cells: principles and applicationsAnnual Review of Biophysics pdf2009
102A. Celedon, I.M. Nodelman, B. Wildt, R. Dewan, P.C. Searson, D. Wirtz, G. D. Bowman, and S.X. SunSingle molecule torque measurements using nanorods in magnetic tweezersNano Letters pdf2009
101B. Wildt, D. Wirtz, and P.C. SearsonProgrammed sub-cellular release for studying the dynamics of cell detachmentNature Methods pdf2009
100B.R. Daniels, E.M. Perkins, T.M. Dobrowsky, S.X. Sun, and D. WirtzAsymmetric enrichment of PIE-1 in the C. elegans zygote is mediated by binary counter-diffusionJournal of Cell Biology pdf2009
99O. Esue, Y. Tseng, and D. Wirtzë±-Actinin and filamin cooperatively enhance the stiffness of actin filament networksPLOS One pdf2009
98S. K. Lai, Y. Wang, R. Cone, D. Wirtz, and J. HanesSelectively altering mucus rheology to "solidify" human mucus at the nanoscalePLOS One pdf2009
97G. Lan, B.R. Daniels, T.M. Dobrowsky, D. Wirtz, and S.X. SunCondensation of FtsZ filaments drives bacterial cell divisionProceedings of the National Academy of Sciences pdf2009
96S.K. Lai, Y.-Y. Wang, D. Wirtz, J. HanesMicro- and macrorheology of mucusAdvanced Drug Delivery Reviews pdf2008
95M.S. Thompson and D. WirtzSensing cytoskeletal mechanics by ballistic intracellular nanorheology (BIN) coupled with cell transfectionMethods in Cell Biology pdf2008
94T.M. Dobrowsky, P. Panorchan, K. Konstantopoulos, and D. WirtzLive-cell single-molecule force spectroscopyMethods in Cell Biology pdf2008
93S. Bajpai, J. Correia, Y. Feng, J. Figueiredo, S.X. Sun, G.D. Longmore, G. Suriano, and D. Wirtzë±-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengtheningProceedings of the National Academy of Sciences pdf2008
92C.M. Hale, A.L. Shrestha, S.B. Khatau, P.J. Stewart-Hutchinson, L. Hernandez, C.L. Stewart, D. Hodzic, and D. WirtzDysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic modelsBiophysical Journal pdf2008
91O. Esue, E.S. Harris, H.N. Higgs, and D. WirtzThe F-actin crosslinking/bundling activity of mammalian forminsJournal of Molecular Biology pdf2008
90G. Lan, A. Dajkovic, D. Wirtz, and S.X. SunPolymerization and bundling kinetics of FtsZ filamentsBiophysical Journal pdf2008
89R.J. Bloom, J. P. George, A. Celedon, S.X. Sun, and D. WirtzMapping local matrix remodeling induced by a migrating tumor cell using 3-D multiple-particle trackingBiophysical Journal pdf2008
88T.M. Dobrowsky, Y. Zhou, S.X. Sun, R.F. Siliciano, and D. WirtzMonitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolutionJournal of Virology pdf2008
87X. Zhou et alFibronectin fibrillogenesis regulates 3-dimensional neovessel formationGenes and Development pdf2008
86P.J. Stewart-Hutchinson, C.M Hale, D. Wirtz, and D. HodzicStructural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffnessExperimental Cell Research pdf2008
85A. Dajkovic, G. Lan, S.X. Sun, D. Wirtz*, and J. LutkenhausMinC spatially controls bacterial cytokinesis by antagonizing the scaffolding function of FtsZCurrent Biology pdf2008
84J.S.H. Lee, C.M. Hale, P. Panorchan, S.B. Khatau, J.P. George, C. L. Stewart, D. Hodzic, and D. WirtzNuclear lamin A/C deficiency induces defects in cell mechanics, polarization and migrationBiophysical Journal pdf2007
83J.Y., Xu, T. Chang, G.E. Inglett, S. Kim, Y. Tseng, and D. WirtzMicro- heterogeneity and micro-rheological properties of high-viscosity oat beta-glucan solutionsFood Chemistry pdf2007
82P. Panorchan, J.S.H. Lee, T.P. Kole, Y. Tseng, and D. WirtzProbing cell mechanics responses to stimuli using ballistic intracellular nanorheologyMethods in Cell Biology pdf2007
81O. Esue, A.A. Carson, Y. Tseng, and D. WirtzA direct interaction between actin and vimentin filaments mediated by the tail domain of vimentinJournal of Biological Chemistry pdf2006
80P. Panorchan, J.S.H. Lee, T.P. Kole, Y. Tseng, and D. WirtzMicrorheology and ROCK signaling of human endothelial cells embedded in a 3D matrixBiophysical Journal pdf2006
79B.R. Daniels, B.C. Masi, and D. WirtzProbing single-cell micromechanics in vivo: the microrheology of C. elegans developing embryosBiophysical Journal pdf2006
78P. Panorcham, J.P. George, and D. WirtzProbing intercellular interactions between vascular endothelial cadherin pairs at single-molecule resolution and in living cellsJournal of Molecular Biology pdf2006
77J. S.H. Lee, P. Panorchan, C.M. Hale, S.B. Khatau, Y. Tseng, and D. WirtzBallistic intracellular nanorheology reveals ROCK-hard stiffening response in to fluid flowJournal of Cell Science pdf2006
76O. Esue, D. Wirtz, and Y. TsengGTPase activity, structure and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreBJournal of Bacteriology pdf2006
75P. Panorchan, M. S. Thompson, K. J. Davis, Y. Tseng, K. Konstantopoulos, and D. WirtzSingle-molecule analysis of cadherin-mediated cell-cell adhesionJournal of Cell Science pdf2006
74S. X. Sun and D. WirtzMechanics of enveloped virus entry into host cellBiophysical Journal pdf2006
73E. Atilgan, D. Wirtz, and S. X. SunMechanics and dynamics of actin-driven thin protrusionsBiophysical Journal pdf2006
72M.I. Chang, P. Panorchan, T. M. Dobrowsky, Y. Tseng, and D. WirtzSingle- molecule analysis of HIV-1 gp120-receptor interactions in living cellsJournal of Virology pdf2005
71E. Atilgan, D. Wirtz and S. X. SunMorphology of the lamellipodium and the organization of actin at the leading edge of crawling cellsBiophysical Journal pdf2005
70O. Esue, Y. Tseng, and D. WirtzMechanical shear can accelerate the gelation of actin filament networksPhysical Review Letters pdf2005
69Y. Tseng, T. P. Kole, J. S. H. Lee, E. Fedorov, S. C. Almo, B. W. Schafer, and D. WirtzHow actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical responseBiochemical and Biophysical Research Communications pdf2005
68O. Esue, Y. Tseng, and D. WirtzThe rapid onset of elasticity during the assembly of the bacterial cell-division protein FtsZBiochemical and Biophysical Research Communications pdf2005
67S.L. Gupton, R.S. Fischer, T.P. Kole, A. Ponti, G. Danuser, S. E. Hitchcock- DeGregori, V.M. Fowler, D. Wirtz, D. Hanein, and C.M. Waterman-StorerCell migration without a lamellipodium: Translation of actin dynamics into cell movement mediated by tropomyosinJournal of Cell Biology pdf2005
66J.S.H. Lee, Y. Tseng, and D. WirtzCdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under shearMolecular Biology of the Cell pdf2005
65O. Esue, M. Cordero, Y. Tseng, and D. WirtzThe assembly of MreB, a prokaryotic 8 homolog of actinJournal of Biological Chemistry pdf2005
64T.P. Kole, Y. Tseng, J.L. Katz, and D. WirtzIntracellular mechanics of migrating fibroblastsMolecular Biology of the Cell pdf2005
63T.P. Kole, Y. Tseng, and D. WirtzIntracellular microrheology as a tool for the measurement of the local mechanical properties of live cellsMethods in Cell Biology pdf2004
62Y. Tseng and D. WirtzDendritic branching and homogenization of actin network mediated by Arp2/3 complexPhysical Review Letters pdf2004
61P. Panorchan, D. Wirtz, and Y. TsengStructure-function relation of biological gels revealed by multiple-particle tracking and DIC microscopy: the case of human lamin networksPhysical Review pdf2004
60P. Panorchan, B. W. Schafer, D. Wirtz, and Y. TsengNuclear envelope breakdown requires overcoming the mechanical integrity of the nuclear laminaJournal of Biological Chemistry pdf2004
59M.G. Klein, W. Shi, Y. Tseng, D. Wirtz, D.R. Kovar, C.J. Straiger, and S.C. AlmoStructure of the actin-crosslinking core of fimbrinStructure pdf2004
58T.P. Kole, Y. Tseng, L. Huang, J.L. Katz, and D. WirtzRho kinase regulates the micromechanical response of adherent cells to Rho activationMolecular Biology of the Cell pdf2004
57W.D. Hanley, D. Wirtz, and K. KonstantopoulosDistinct kinetic and mechanical properties govern selectin-leukocyte interactionsJournal of Cell Science pdf2004
56M. Dawson, E. Krauland, D. Wirtz, and J. HanesTransport of polymeric nanoparticles gene carriers in gastric mucusBiotechnology Progress pdf2004
55Y. Tseng, J.S.H. Lee, T.P. Kole, I. Jiang, and D. WirtzMicro-organization and visco-elasticity of the nucleus revealed by particle nanotrackingJournal of Cell Science pdf2004
54S.R. Heidemann and D. WirtzTowards a regional approach to cell mechanicsTrends in Cell Biology pdf2004
53J. Suh, D. Wirtz, and J. HanesReal-time intracellular transport phenomena of gene nanocarriers studied by multiple particle trackingBiotechnology Progress pdf2004
52Y. Tseng, K.M. An, O. Esue, and D. WirtzThe bimodal role of filamin in controlling the architecture and mechanics F-actin networksJournal of Biological Chemistry pdf2004
51M. Dawson, D. Wirtz, and J. HanesEnhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transportJournal of Biological Chemistry pdf2003
50K. Konstantopoulos, W. Hanley, and D. WirtzReceptor/ligand binding: ‰ÛÏcatch‰Û bonds finally captured experimentallyCurrent Biology pdf2003
49Y. Zhou, D. Wirtz, and G. ChirikjianDetermining the Gaussian probability distribution of the best-fit ellipsoid of revolution for a polymer chain from planar projectionsInverse Problems pdf2003
48S. Yamada, D. Wirtz, and P.A. CoulombeThe mechanical properties of simple epithelial keratin 8 and 18: Discriminating between interfacial and bulk elasticitiesJournal of Structural Biology pdf2003
47W. Hanley, O. McCarty, S. Jadhav, Y. Tseng, D. Wirtz, and K. KonstantopoulosSingle-molecule characterization of P-selectin/ligand bindingJournal of Biological Chemistry pdf2003
46H.Y. Li, D. Wirtz, and Y. ZhengA mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivoJournal of Cell Biology pdf2003
45J. Suh, D. Wirtz, and J. HanesEffective active transport of gene nanocarriers to the cell nucleusProceedings of the National Academy of Sciences pdf2003
44Y. Tseng, T. P. Kole, and D. WirtzMicromechanical mapping of live cells by multiple particle tracking microrheologyBiophysical Journal pdf2002
43Y. Tseng, T. P. Kole, S.-H. J. Lee, and D. WirtzLocal dynamics and viscoelastic properties of cell biological systemsCurrent Opinion in Colloid & Interface Science pdf2002
42A. Goodman, Y. Tseng, and D. WirtzEffect of length, topology, and concentration on the microviscosity and microheterogeneity of DNA solutionsJournal of Molecular Biology pdf2002
41A. Rahman, Y. Tseng, and D. WirtzMicromechanical coupling between surface cell receptors and RGD peptidesBiochemical and Biophysical Research Comm. pdf2002
40Y. Tseng, B.W. Schafer, S.C. Almo, and D. WirtzFunctional synergy of actin filament crosslinking proteinsJournal of Biological Chemistry pdf2002
39Y. Tseng, K.M. An, and D. WirtzMicroheterogeneity controls the rate of gelation of actin filament networksJournal of Biological Chemistry pdf2002
38J. Xu, Y. Tseng, C.J. Carriere, and D. WirtzMicroheterogeneity and microrheology of wheat gliadin suspensions studied by multiple particle trackingBiomacromolecules pdf2002
37S. Yamada, D. Wirtz, and P.A. CoulombePairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filamentsMolecular Biology of the Cell pdf2002
36O. Bousquet, L. Ma, S. Yamada, C. Gu, T. Idei, K. Takahashi, D. Wirtz, and P.A. CoulombeThe non-helical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitroJournal of Cell Biology pdf2001
35Y. Tseng and D. WirtzMechanics and multiple particle tracking micro- heterogeneity of ë±-actinin crosslinked actin filament networksBiophysical Journal pdf2001
34Y. Tseng, E. Fedorov, M. McCaffery, S.C. Almo, and D. WirtzMicromechanics and ultrastructure of actin filament networks crosslinked by fascin: A comparison with ë±-actininJournal of Molecular Biology pdf2001
33L. Ma, S. Yamada, D. Wirtz, and P.A. CoulombeA "hot-spot" mutation alters the mechanical properties of keratin filament networksNature Cell Biology pdf2001
32J. Xu, J.A. Bietz, F.C. Felker, and D. WirtzRheological properties of vital wheat gluten suspensionsCereal Chemistry pdf2001
31C. Haber and D. WirtzMagnetic tweezers for DNA micromanipulationReview of Scientific Instruments pdf2000
30P.A. Coulombe, O. Bousquet, L. Ma, S. Yamada, and D. WirtzThe "ins" and "outs" of intermediate filament organizationTrends in Cell Biology pdf2000
29J. Xu, Y. Tseng, and D. WirtzStrain-hardening of actin filament networks: regulation by the dynamic crosslinking protein ë±-actininJournal of Biological Chemistry pdf2000
28C. Haber, S.A. Ruiz, and D. WirtzShape anisotropy of a single random-walk polymerProceedings of the National Academy of Sciences pdf2000
27C. Haber and D. WirtzShear-induced ëÈ-phage DNA assemblyBiophysical Journal pdf2000
26J. Apgar, Y. Tseng, E. Fedorov, M.B. Herwig, S.C. Almo, D. WirtzMultiple- particle tracking measurements of the heterogeneities of solutions of actin filaments and actin bundlesBiophysical Journal pdf2000
25S. Yamada, D. Wirtz, and S.C. KuoMechanics of living cells measured by laser tracking microrheology (LTM)Biophysical Journal pdf2000
24L. Ma, J. Xu, P.A. Coulombe, and D. WirtzEpidermal keratin suspensions show unique micromechanical propertiesJournal of Biological Chemistry pdf1999
23P. Leduc, C. Haber, G. Bao, and D. WirtzDynamics of individual flexible polymers in a shear flowNature pdf1999
22A. Palmer, J. Xu, S.C. Kuo, and D. WirtzDiffusing wave spectroscopy microrheology of actin filament networksBiophysical Journal pdf1999
21K. Rufener, A. Palmer, J. Xu, and D. WirtzHigh-frequency dynamics and microrheology of macromolecular solutions measured by diffusing wave spectroscopy: the case of actin filament networksJournal of Non-Newtonian Fluid Mechanics pdf1999
20J. Xu, D. Wirtz, and T.D. PollardDynamic crosslinking by ë±-actinin determines the mechanical properties of actin filament networksJournal of Biological Chemistry pdf1998
19A. Palmer, B. Cha, and D. WirtzEffect of Latrunculin A on the rheology of actin filament networksJournal of Polymer Science pdf1998
18J. Xu, A. Palmer, and D. WirtzRheology and microrheology of semiflexible polymer solutionsMacromolecules pdf1998
17W. Petka, J.H. Harden, J. McGrath, D. Wirtz, and D.A. TirrellReversible hydrogels from self-assembling artificial proteinsScience pdf1998
16A. Silva and D. WirtzDominant mode of diffusion in the self-similar phase separation of a magnetic fluidLangmuir pdf1998
15J. Xu, V. Viasnoff, and D. WirtzCompliance of actin filament networks measured by diffusing wave spectroscopyRheologica Acta pdf1998
14A. Palmer, J. Xu, and D. WirtzHigh-frequency viscoelasticity of crosslinked actin filament networks measured by diffusing wave spectroscopyRheologica Acta pdf1998
13T.G. Mason, A. Dhople, and D. WirtzLinear viscoelastic moduli of concentrated DNA solutionsMacromolecules pdf1998
12T.G. Mason, A. Dhople, and D. WirtzConcentrated DNA rheology and microrheologyMRS Proceedings pdf1997
11T.G. Mason, K. Ganesan, J. van Zanten, D. Wirtz, S.C. KuoParticle-tracking microrheology of complex fluidsPhysical Review Letters pdf1997
10A. Silva, Bond, R., Plouraboue, F., and Wirtz, DThe fluctuation dynamics of a single magnetic chainPhysical Review E pdf1996
9G.G. Fuller, J.W. van Egmond, D. Wirtz, E. Peuvrel-Didier, E. Wheeler, and H. TakahashiEnhancement of concentration fluctuations by external fieldsACS Symposium Series pdf1995
8D. WirtzDirect measurement of the transport properties of a single DNA moleculePhysical Review Letters pdf1995
7D. Wirtz and M. FermigierPeriodic structures and substructures in magnetic suspensionsLangmuir pdf1995
6D. Wirtz and M. FermigierOne-dimensional patterns and wavelength selection in magnetic fluidsPhysical Review Letters pdf1994
5D. WirtzFlow-induced scattering peak in the structure factor of polymer solutionsPhysical Review E pdf1994
4D. WirtzFluctuation enhancement and reduction in sheared polymer solutionsMacromolecules pdf1994
3D. Wirtz, K. Berend, and G.G. FullerElectric-field-induced structure in polymer solutions near the critical pointMacromolecules pdf1992
2D. Wirtz, D.E. Werner, and G.G. FullerStructure and optical anisotropies of critical polymer solutions in electric fieldsJournal of Chemical Physics pdf1994
1D. Wirtz and G.G. FullerPhase transitions induced by electric fields in near-critical polymer solutionsPhysical Review Letters pdf1993